Diseases of autoimmune origin usually exhibit the following features:

1. An elevated level of immunoglobulins.
2. Demonstrable antibodies.
3. Deposition of immunoglobulins or their derivatives at sites of election, such as renal glomeruli.
4. Accumulation of lymphocytes and plasma cells at the sites of lesion.
5. Benefit from corticosteroid or other immunosuppressive therapy.
6. The occurrence of more than one type of autoimmune lesion in an individual.
7. A genetic predisposition towards autoimmunity.
8. Incidence higher among females.
9. Chronicity, Usually nonreversible.