ADMET
absorption, distribution, metabolism, elimination, toxicology

Allele
Short for "allelomorph"; different forms of a gene that can exist at a single locus; the alleles might differ in DNA sequence and also affect the functioning of a single product.

Allele frequency
Describes the commonness of an allele in a given population, i.e. the percentage of all alleles at a given locus in a population gene pool represented by a particular allele.

Amino acid
Building block of proteins; around 20 amino acids are present in proteins: alanine, arginine, asparagine, aspartic acid, cysteine, glutamic acid, glutamine, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, proline, serine, threonine, tryptophan, tyrosine, valine.

Amplicon
A stretch of DNA that has been specifically amplified by PCR

Antibody
An inducible immunoglobulin protein that is produced by the B lymphocytes of the immune system. It recognizes and binds to a specific antigen molecule of a foreign substance introduced into the organism. Upon binding to corresponding antigens, the antibodies set in motion a process to eliminate the antigens.

Antigen
Any foreign substance (self - non-self discrimination), such as virus, bacterium, or protein. After introduction into an organism, the antigenic substances elicit an immune response by stimulating the production of specific antibodies.

Aptamer
DNA or RNA molecule which has been artificially manipulated to allow binding with other molecules and viruses.

Array technology
In a broader context, array technology refers to computer science, engineering and also telecomminications. The technology may involve 2D gel electrophoresis, CCDs, detection technologies, fiber optics, imaging, ink jetting, mass spectrometry, photolithography, phosphorimagers, piezoelectric, semiconductors and spotting robots.

Arrayer
Robot for making microarrays. The robot transfers clones from microwell plates to microscope slides.

Association Study
Study that compares DNA samples from populations of individuals with and without a specific clinical trait

BAC
Stands for Bacterial Artificial Chromosome, a cloning and sequencing vector derived form a bacterial chromosome into which a 100,000 bp fragment or more can be inserted.

BioChip
Miniaturised substrates onto which a large number of biomolecules are attached with high density and in a defined microarray.

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